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Identification of novel ER-α target genes in breast cancer cells: gene- and cell-selective co-regulator recruitment at target promoters determines the response to 17β-estradiol and tamoxifen

机译：乳腺癌细胞中新的ER-α靶基因的鉴定：在靶启动子处募集基因和细胞选择性的共调节子决定了对17β-雌二醇和他莫昔芬的反应

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International audience

机译：国际观众

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Romano, Andrea; Adriaens, Michiel; Kuenen, Sabine; Delvoux, Bert; Dunselman, Gerard; Evelo, Chris; Groothuis, Patrick;
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年度 2009
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1. Identification of novel ER-alpha target genes in breast cancer cells: gene- and cell-selective co-regulator recruitment at target promoters determines the response to 17beta-estradiol and tamoxifen. [J] . Romano A, Adriaens M, Kuenen Molecular and Cellular Endocrinology . 2010,第1期

机译：乳腺癌细胞中新的ER-alpha靶基因的鉴定：在靶启动子处的基因和细胞选择性共调节子募集决定了对17β-雌二醇和他莫昔芬的反应。
2. Identification of PUMA as an estrogen target gene that mediates the apoptotic response to tamoxifen in human breast cancer cells and predicts patient outcome and tamoxifen responsiveness in breast cancer [J] . C G Roberts, E K A Millar, S A OToole, Oncogene . 2011,第28期

机译：鉴定PUMA作为雌激素靶基因的介质，介导人乳腺癌细胞中的毒素反应，并预测患者结果和乳腺癌的反应性
3. Expression of both estrogen receptor-beta 1 (ER-β1) and its co-regulator steroid receptor RNA activator protein (SRAP) are predictive for benefit from tamoxifen therapy in patients with estrogen receptor-alpha (ER-α)-negative early breast cancer (EBC) [J] . YanY., LiX., BlanchardA., Annals of oncology: official journal of the European Society for Medical Oncology . 2013,第8期

机译：雌激素受体-α1（ER-β1）阴性的早期乳腺癌患者中雌激素受体-β1（ER-β1）及其共调节类固醇受体RNA激活蛋白（SRAP）的表达可预测他莫昔芬疗法的获益（EBC）
4. Breast Cancer-specific Delivery of Therapeutic microRNA with Novel Breast Cancer-targeting Cell Penetrating Peptide-conjugated Gene Carrier [C] . Hwa Jeong Lee, Ran Namgung, Won Jong Kim, World biomaterials congress . 2012

机译：新型靶向乳腺癌的细胞穿透肽偶联基因载体与治疗性microRNA的乳腺癌特异性递送。
5. Identification of LRP8, CDCA7, and MLK4 as Novel Therapeutic Targets for Cancer Stem Cells in Triple-negative Breast Cancer [D] . Lin, Chang-Ching. 2018

机译：鉴定LRP8，CDCA7和MLK4作为三阴性乳腺癌中癌症干细胞的新疗法靶标
6. Effects of 17β-estradiol and tamoxifen on gastric cancer cell proliferation and apoptosis and ER-α36 expression [O] . Xuming Wang, Qiuyue Chen, Xuan Huang, -1

机译：17β-雌二醇和他莫昔芬对胃癌细胞增殖和凋亡及ER-α36表达的影响
7. Identification of novel ER-alpha target genes in breast cancer cells: Gene- and cell-selective co-regulator recruitment at target promoters determines the response to 17beta-estradiol and tamoxifen [O] . Romano, A., Michiel Adriaens, M.E., Kuenen, S., 2010

机译：乳腺癌细胞中新的ER-alpha靶基因的鉴定：靶启动子处的基因和细胞选择性共调节子募集决定了对17beta-雌二醇和他莫昔芬的反应
8. Identification of the Downstream Promoter Targets of Smad Tumor Suppressors in Human Breast Cancer Cells [R] . Liu, X. 2006

机译：人乳腺癌细胞中smad肿瘤抑制因子下游启动子靶标的鉴定

Identification of novel ER-α target genes in breast cancer cells: gene- and cell-selective co-regulator recruitment at target promoters determines the response to 17β-estradiol and tamoxifen

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